What to Expect in the First Few Weeks?
The first few weeks are all about helping your body adjust. When you begin GLP-1 medications like Semaglutide or Tirzepatide, your provider will start you on a low dose to minimize side effects. During this phase, the goal is to ease into the treatment, not to see dramatic weight changes right away.
Some patients notice reduced appetite within the first 7 to 10 days. Meals may feel more filling, and cravings for sugar or late-night snacks might naturally decrease. Even if the number on the scale hasn’t moved much yet, these internal shifts are strong early signs that the medication is working.
Dr. Michael Moran reminds patients that real transformation is a process. The body is learning a new rhythm, and every week builds on the last.
When Does Visible Weight Loss Begin?
For most patients, noticeable weight loss starts between weeks 3 and 6. This is when the appetite regulation effect is more consistent, and meal portions begin to shrink without much effort.
If you’re following the Silhouette MD program, which includes meal planning, mindset coaching, and provider check-ins, you’re likely to start seeing changes in the way your clothes fit, your energy levels, and even your mood.
In clinical studies, patients using Semaglutide lost up to 5 percent of their body weight within the first two months. With continued treatment and lifestyle changes, that number often doubles or triples over the following months.
Factors That Impact Your Timeline
No two journeys look exactly the same. While some people see progress quickly, others may notice changes more gradually. Several factors can affect how soon you’ll see results:
- Your starting weight and BMI
- How your body responds to the medication
- Your dosage schedule and adjustments
- Nutritional choices and physical activity
- Stress levels, sleep quality, and other health conditions
Dr. Michael Moran emphasizes that the most successful patients focus on consistency over speed. While weight loss might not happen overnight, small, steady progress leads to the best long-term outcomes.
The Power of Consistency Over 3 to 6 Months
By the three-month mark, many patients have lost between 10 and 15 pounds, sometimes more. Appetite has become easier to manage, habits are becoming second nature, and the body is burning stored fat more efficiently.
Around months four to six, results tend to become even more noticeable. Muscle tone improves, inflammation decreases, and confidence builds. This is often when patients feel their best, not just physically, but emotionally as well.
Silhouette MD’s program is structured to guide you through each of these phases, offering continued support from your provider, coach, and care team. You’re never doing this alone.
What If You Don’t See Results Right Away?
It’s completely normal to feel discouraged if your progress feels slow in the beginning. But in nearly every case, the results do come, sometimes just on a slightly delayed timeline.
Here’s what we recommend if your progress feels stalled:
- Stay in close communication with your provider
- Keep track of meals, energy, and digestion
- Focus on non-scale victories like reduced cravings or better sleep
- Be patient with dose increases and trust the process
Dr. Michael Moran often tells patients that the scale is just one part of the story. Fat loss, hormone balance, improved energy, and better relationship with food are all signs of success, even before big weight changes appear.
Conclusion
Weight loss injections are not a quick fix, but they are highly effective when used correctly. Most people begin seeing changes within the first month, with visible results becoming more noticeable between weeks 4 and 8. By month 3, your momentum is strong, and the changes become lasting.
About the Author
Dr. Michael Moran
Michael founded Silhouette MD to achieve real, lasting transformation. With a background in finance, healthcare, and tech, he combines a results-driven approach with a personal mission rooted in his own journey of discipline and self-discovery.
Proven Results.